Computational search for the interactors of alternatively spliced TREM2 isoforms
The predicted interaction of CD9 or CALM with TREM2 isoforms suggests a possible role of TREM2 in cell adhesion and calcium regulation. Both cell adhesion and calcium regulation are two biological systems previously implicated in Alzheimer's disease.
Authors
- Aditya Menon
- Lynn M. Bekris (ORCID: https://orcid.org/0000-0002-2747-7672)
- Junyi Liang (ORCID: https://orcid.org/0009-0000-3011-5819)
- Taylor Tomco
Institutions
- Cleveland Clinic Lerner College of Medicine (US)
- Case Western Reserve University (US)
- Western University of Health Sciences (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2024-12-01
- DOI
- https://doi.org/10.1002/alz.086570
- Primary Topic
- Polyoxometalates: Synthesis and Applications
- Type
- article
- Field-Weighted Citation Impact
- 0.00