Ferroptosis programmed cell death in AD‐derived neurons

Understand the role of iron accumulation, oxidative stress, and cell-specific susceptibility to ferroptosis programmed cell death in human brain cells and model the complex molecular responses related to neuronal loss in AD. These experiments provide the kinetics of biochemical, metabolic and morphological features of AD neurons under ferroptotic oxidative stress.

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Publication Details

Journal
Alzheimer s & Dementia
Published
2024-12-01
DOI
https://doi.org/10.1002/alz.089791
Primary Topic
Extracellular vesicles in disease
Type
article
Field-Weighted Citation Impact
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article

Ferroptosis programmed cell death in AD‐derived neurons

Germán Plascencia‐Villa, George Perry
Alzheimer s & Dementia
Extracellular vesicles in disease
article

Ferroptosis programmed cell death in AD‐derived neurons

Germán Plascencia‐Villa, George Perry
article en

Abstract

Understand the role of iron accumulation, oxidative stress, and cell-specific susceptibility to ferroptosis programmed cell death in human brain cells and model the complex molecular responses related to neuronal loss in AD. These experiments provide the kinetics of biochemical, metabolic and morphological features of AD neurons under ferroptotic oxidative stress.

Alzheimer s & DementiaVol. 20(S1)
The University of Texas at San Antonio (US)
Openalex Percentile: Top 78%
Extracellular vesicles in disease
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Ferroptosis programmed cell death in AD‐derived neurons — Germán Plascencia‐Villa, George Perry · Alzheimer s & Dementia (2024) | TGRS Research Map | TGRS