Evaluating the Impact of Combined Clinical and Genetic Risk Factors on Dementia Onset
The majority of our cohort exhibited at least one dementia risk indicator, with a higher risk burden markedly increasing dementia risk. These findings underscore the value of integrating genetic and clinical risk factors in predicting dementia, highlighting the potential of precision medicine in guiding preventive strategies for at-risk individuals.
Authors
- Alan E. Renton (ORCID: https://orcid.org/0000-0001-6702-8268)
- Shea J. Andrews (ORCID: https://orcid.org/0000-0002-1921-9470)
- Kristine S. Yaffe (ORCID: https://orcid.org/0000-0003-0919-3825)
- Jennifer S. Yokoyama (ORCID: https://orcid.org/0000-0001-7274-2634)
- Brian Fulton‐Howard (ORCID: https://orcid.org/0000-0002-9788-3115)
- Caroline Warly Solsberg
Institutions
- University of California, San Francisco (US)
- Icahn School of Medicine at Mount Sinai (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2024-12-01
- DOI
- https://doi.org/10.1002/alz.086576
- Primary Topic
- Dementia and Cognitive Impairment Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00