Unveiling the role of Fli‐1 in controlling astrocyte dysfunction and transformation in Alzheimer’s disease
The elevated Fli-1 levels contribute to astrocyte dysfunction and A1 astrocyte transformation in AD. Targeting Fli-1 could be a therapeutic approach to prevent or mitigate AD-induced astrocyte dysfunction and cognitive impairment, offering potential clinical applications.
Authors
- Andrew Goodwin (ORCID: https://orcid.org/0000-0002-6543-9458)
- Hongkuan Fan (ORCID: https://orcid.org/0000-0002-9441-9405)
- Perry V. Halushka (ORCID: https://orcid.org/0000-0002-6836-3647)
- Pengfei Li (ORCID: https://orcid.org/0000-0001-6436-4573)
Institutions
- Medical University of South Carolina (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2024-12-01
- DOI
- https://doi.org/10.1002/alz.086131
- Citations
- 1
- Primary Topic
- Alzheimer's disease research and treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.33