Copy number variation of whole genome sequence in 1519 patients with Alzheimer’s disease in China
Overall, our findings suggest that the occurrence of APP locus duplication appears to be less common in the Chinese population. Other rare CNV variants in dementia genes may have potentially pathogenic and further validation of their pathogenicity is needed.
Authors
- Bin Jiao (ORCID: https://orcid.org/0000-0002-6337-0784)
- Tianyan Xu
- Lu Shen (ORCID: https://orcid.org/0000-0002-3393-8578)
- Yuan Zhu (ORCID: https://orcid.org/0000-0001-9419-6291)
- Qijie Yang
- Xuewen Xiao
Institutions
- Central South University (CN)
- Xiangya Hospital Central South University (CN)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2024-12-01
- DOI
- https://doi.org/10.1002/alz.087393
- Primary Topic
- Genomic variations and chromosomal abnormalities
- Type
- article
- Field-Weighted Citation Impact
- 0.00