Genetic Risks of AD and Associated Health Conditions are Linked with the Dynamic Patterns of AD’s Clinical and Physiological Course

This study unveils the relationship between genetic risk scores for health conditions and nuanced aspects of AD progression. We show that despite being established on case/control cohorts, these genetic risk scores offer valuable insights into the finer dynamics of disease progression. References: [1] Nedelec et al., Identifying health conditions associated with Alzheimer's disease up to 15 years before diagnosis: an agnostic study of French and British health records, in Lancet Digital Health, 2022 [2] Fournier and Durrleman, A Multimodal Disease Progression Model for Genetic Associations with Disease Dynamics, in MICCAI 2023.