Extracellular‐Vesicle mediated pyroptosis leads to gut‐brain axis after stroke in a mouse model of Alzheimer’s Disease

Taken together these results indicate an important role for EV signaling and pyroptosis in disruption of the bidirectional gut-brain axis after stroke in aged 3xTg mice in an animal model of stroke.

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Publication Details

Journal
Alzheimer s & Dementia
Published
2024-12-01
DOI
https://doi.org/10.1002/alz.089237
Primary Topic
Inflammasome and immune disorders
Type
article
Field-Weighted Citation Impact
0.00
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article

Extracellular‐Vesicle mediated pyroptosis leads to gut‐brain axis after stroke in a mouse model of Alzheimer’s Disease

Winston Walters, Nadine Kerr, W. Dalton Dietrich, Juliana Sanchez‐Molano et al.
Alzheimer s & Dementia
Inflammasome and immune disorders
article

Extracellular‐Vesicle mediated pyroptosis leads to gut‐brain axis after stroke in a mouse model of Alzheimer’s Disease

Winston Walters, Nadine Kerr, W. Dalton Dietrich, Juliana Sanchez‐Molano, Robert W. Keane, Helen M. Bramlett, Juan Pablo de Rivero Vaccari
article en

Abstract

Taken together these results indicate an important role for EV signaling and pyroptosis in disruption of the bidirectional gut-brain axis after stroke in aged 3xTg mice in an animal model of stroke.

Alzheimer s & DementiaVol. 20(S1)
University of Miami (US), Bruce W. Carter VA Medical Center (US)
Good health and well-being
Openalex Percentile: Top 78%
Inflammasome and immune disorders
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