Cellular overexpression of mutant TDP‐43 results in a decrease in solubility of phosphorylated TDP‐43
This cellular overexpression model shows a change in solubility and aggregation of phosphorylated TDP-43. Hopefully this model will provide a better understanding of the pathogenesis of TDP-43 proteinopathies.
Authors
- Matthew B Dopler (ORCID: https://orcid.org/0000-0002-9708-8090)
- Michael A. Gitcho (ORCID: https://orcid.org/0000-0002-9223-5426)
- Sanaz Arezoumandan (ORCID: https://orcid.org/0000-0001-6569-9009)
- Muhammad Abeer
- Keyshawn Cox
- Juneessa M Pressley
- Tyler L. Petersen
Institutions
- Delaware State University (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2024-12-01
- DOI
- https://doi.org/10.1002/alz.090006
- Primary Topic
- Amyotrophic Lateral Sclerosis Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00