Known and novel genes significant to AD across tissues may help to uncover comprehensive changes of disease
In addition to known APOE region genes, novel genes with implications relevant to AD etiology and ties to other immune, vascular, and neurological diseases also appeared significant across tissues. Next we will investigate how these gene expression changes apply to pathways within relevant tissues.
Authors
- Rasika Venkatesh (ORCID: https://orcid.org/0009-0003-4471-4291)
- Anni Moore (ORCID: https://orcid.org/0000-0003-1953-6449)
- Rachit Kumar (ORCID: https://orcid.org/0000-0002-7736-3307)
- Manu Shivakumar (ORCID: https://orcid.org/0000-0003-4733-7375)
- Dokyoon Kim (ORCID: https://orcid.org/0000-0002-4592-9564)
- Li Shen
- Marylyn D. Ritchie
- Yuki Bradford
- Jingxuan Bao
Institutions
- University of Pennsylvania (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2024-12-01
- DOI
- https://doi.org/10.1002/alz.087088
- Citations
- 1
- Primary Topic
- Genetic Associations and Epidemiology
- Type
- article
- Field-Weighted Citation Impact
- 0.55