Correlation between FNDC5 expression and tau pathology in elderly individuals

These results suggest that FNDC5 expression in hippocampus is reduced with tau pathology in humans, encouraging further studies to explore how physical exercise and FNDC5/irisin may influence tau pathology during aging.

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Publication Details

Journal
Alzheimer s & Dementia
Published
2024-12-01
DOI
https://doi.org/10.1002/alz.087798
Primary Topic
Neuroinflammation and Neurodegeneration Mechanisms
Type
article
Field-Weighted Citation Impact
0.00
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article

Correlation between FNDC5 expression and tau pathology in elderly individuals

Mychael V. Lourenco, Ícaro Raony
Alzheimer s & Dementia
Neuroinflammation and Neurodegeneration Mechanisms
article

Correlation between FNDC5 expression and tau pathology in elderly individuals

Mychael V. Lourenco, Ícaro Raony
article en

Abstract

These results suggest that FNDC5 expression in hippocampus is reduced with tau pathology in humans, encouraging further studies to explore how physical exercise and FNDC5/irisin may influence tau pathology during aging.

Alzheimer s & DementiaVol. 20(S1)
Universidade Federal do Rio de Janeiro (BR), Universidade Federal Fluminense (BR), Hospital Universitário Antônio Pedro (BR)
Reduced inequalities
Openalex Percentile: Top 72%
Neuroinflammation and Neurodegeneration Mechanisms
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