Deciphering how ApoE shapes neurodevelopment

It is crucial to understand the developmental roles of ApoE and the isoform-specific differences in its functions to better understand its function and dysfunction. Indeed, we find the effects of E4 extend beyond proteins considered central to AD pathology. Our results add to the growing body of literature on altered course of neurodevelopment from genetic risk factors in AD.

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Publication Details

Journal
Alzheimer s & Dementia
Published
2024-12-01
DOI
https://doi.org/10.1002/alz.090731
Primary Topic
Alzheimer's disease research and treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

Deciphering how ApoE shapes neurodevelopment

Reeteka Sud
Alzheimer s & Dementia
Alzheimer's disease research and treatments
article

Deciphering how ApoE shapes neurodevelopment

Reeteka Sud
article en

Abstract

It is crucial to understand the developmental roles of ApoE and the isoform-specific differences in its functions to better understand its function and dysfunction. Indeed, we find the effects of E4 extend beyond proteins considered central to AD pathology. Our results add to the growing body of literature on altered course of neurodevelopment from genetic risk factors in AD.

Alzheimer s & DementiaVol. 20(S1)
National Institute of Mental Health and Neurosciences (IN)
Openalex Percentile: Top 65%
Alzheimer's disease research and treatments
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Deciphering how ApoE shapes neurodevelopment — Reeteka Sud · Alzheimer s & Dementia (2024) | TGRS Research Map | TGRS