The Role of diet x gene interaction in LOAD2.Plcg2<sup>M28L</sup> mice
Our findings provide evidence that Plcg2 plays an important role in LOAD and the addition of Plcg2<sup>M28L</sup> to a sensitized LOAD model (LOAD2) more closely align phenotypes in the mouse to outcomes observed in human AD.
Authors
- Gareth R. Howell (ORCID: https://orcid.org/0000-0003-0565-6474)
- Gregory W. Carter (ORCID: https://orcid.org/0000-0002-2834-8186)
- Bruce T. Lamb (ORCID: https://orcid.org/0000-0001-8507-2561)
- Cynthia M. Ingraham
- Adrian L. Oblak (ORCID: https://orcid.org/0000-0003-1210-8791)
- Stacey J. Sukoff Rizzo (ORCID: https://orcid.org/0000-0002-1460-8127)
- Michael Sasner (ORCID: https://orcid.org/0000-0002-6612-6111)
- Paul R. Territo (ORCID: https://orcid.org/0000-0003-0460-332X)
- Claudia Rangel‐Barajas (ORCID: https://orcid.org/0000-0002-4818-8247)
- Christopher D Lloyd
Institutions
- University of Pittsburgh (US)
- Neurosciences Institute (US)
- Indianapolis Zoo (US)
- Jackson Laboratory (US)
- Indiana University School of Medicine
- Indiana University – Purdue University Indianapolis (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2024-12-01
- DOI
- https://doi.org/10.1002/alz.091334
- Citations
- 1
- Primary Topic
- Alzheimer's disease research and treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.33