HSV1 infection elicits distinct immune responses in microglia and macrophages
Macrophages exhibit an enhanced inflammatory response in contrast to microglia upon HSV1 infection and an opposite reaction in Abeta1-42 uptake. Our findings indicate distinct responses of these two cell types to HSV1 infection, providing novel insight into our understanding of their unique tissue-specific roles.
Authors
- Chitra Mohinder Singh Singal (ORCID: https://orcid.org/0000-0001-6170-0500)
- Elizabeth M. Bradshaw (ORCID: https://orcid.org/0000-0002-6766-4325)
- Wassim Elyaman (ORCID: https://orcid.org/0000-0001-7238-374X)
Institutions
- Columbia University Irving Medical Center (US)
- Columbia University (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2024-12-01
- DOI
- https://doi.org/10.1002/alz.092417
- Primary Topic
- Herpesvirus Infections and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00