Defects in the signaling lipid PI3P may contribute to dendritic spine loss in Alzheimer’s disease
Continued studies of the connections between PI3P, spine density and AD may ultimately open avenues for new therapeutic approaches for this devastating disease.
Authors
- Michael A. Sutton (ORCID: https://orcid.org/0000-0002-0692-6459)
- Tunahan Uygun (ORCID: https://orcid.org/0000-0002-8199-702X)
- Pilar Rivero-Ríos (ORCID: https://orcid.org/0000-0001-9398-2995)
- Garrett D. Chavis (ORCID: https://orcid.org/0000-0001-5379-4180)
- Lois S. Weisman (ORCID: https://orcid.org/0000-0001-7740-9785)
Institutions
- University of Michigan (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2024-12-01
- DOI
- https://doi.org/10.1002/alz.086935
- Primary Topic
- Cellular transport and secretion
- Type
- article
- Field-Weighted Citation Impact
- 0.00