Rescue of impaired hippocampal consolidation in the APP/PS1 mouse model of Alzheimer’s disease after increasing cerebral blood flow
We found that increasing CBF normalizes neural mechanisms of memory consolidation that are altered in AD mouse models, supporting the development of treatment approaches to increase CBF in AD.
Authors
- Ryan E. Harvey (ORCID: https://orcid.org/0000-0002-4622-4494)
- Jun Shimizu (ORCID: https://orcid.org/0000-0002-6461-4648)
- Azahara Oliva (ORCID: https://orcid.org/0000-0003-1206-7125)
- Ralitsa Todorova (ORCID: https://orcid.org/0000-0003-2238-0297)
- Laura E. Berkowitz (ORCID: https://orcid.org/0000-0002-4285-2995)
- Nozomi Nishimura (ORCID: https://orcid.org/0000-0003-4342-9416)
- Antonio Fernández‐Ruiz (ORCID: https://orcid.org/0000-0001-8481-0796)
- Chris B. Schaffer (ORCID: https://orcid.org/0000-0002-7800-9596)
- Xuebin Dong (ORCID: https://orcid.org/0000-0002-6907-0491)
Institutions
- Cornell University (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2024-12-01
- DOI
- https://doi.org/10.1002/alz.088977
- Primary Topic
- Neuroscience and Neuropharmacology Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00