BrainNetScore: Enhancing Alzheimer’s disease risk prediction using genetic‐guided brain volumetric phenotype network
BrainNetScore significantly improves AD risk prediction when combined with PRSs. This highlights the potential of network-based approaches and comprehensive genetic analysis in developing personalized medicine strategies for AD. Future work should extend this model to diverse populations.
Authors
- Sang‐Hyuk Jung (ORCID: https://orcid.org/0000-0003-4116-3327)
- Jakob Woerner
- Yonghyun Nam (ORCID: https://orcid.org/0000-0003-2963-2151)
- Haochang Shou
- Erica H Suh
- Dokyoon Kim (ORCID: https://orcid.org/0000-0002-4592-9564)
- Li Shen (ORCID: https://orcid.org/0009-0006-2736-0892)
Institutions
- University of Pennsylvania (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2024-12-01
- DOI
- https://doi.org/10.1002/alz.084351
- Primary Topic
- Brain Tumor Detection and Classification
- Type
- article
- Field-Weighted Citation Impact
- 0.00