Mapping the neuroimmune landscape of Alzheimer’s disease in African Americans
While microglia in the cortex and white matter of older AA donors acquire the same functional phenotypes as microglia in the brains of NHW donors, they display a distinct population structure. Our findings underline the importance of studying the neuroimmune compartment of AD specifically in AAs.
Authors
- Vilas Menon (ORCID: https://orcid.org/0000-0002-4096-8601)
- Julie A. Schneider (ORCID: https://orcid.org/0000-0002-9482-1752)
- Lisa L. Barnes (ORCID: https://orcid.org/0000-0002-0072-9817)
- Peter Canoll (ORCID: https://orcid.org/0000-0002-7001-0226)
- Emily Lee
- Marta Olah
- Naren Nimmagadda (ORCID: https://orcid.org/0000-0003-1845-9891)
- Nkechime Ifediora
- David A. Bennett
Institutions
- Rush University Medical Center (US)
- Columbia University Irving Medical Center (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2024-12-01
- DOI
- https://doi.org/10.1002/alz.091633
- Primary Topic
- Neuroinflammation and Neurodegeneration Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 0.00