Xenografted human microglia display diverse transcriptomic states in response to Alzheimer’s disease‐related Aβ pathology

We have identified multiple transcriptomic cell states adopted by microglia in response to AD-related pathology, which should be taken into account in translational studies.

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Publication Details

Journal
Alzheimer s & Dementia
Published
2024-12-01
DOI
https://doi.org/10.1002/alz.090394
Citations
2
Primary Topic
Neuroinflammation and Neurodegeneration Mechanisms
Type
article
Field-Weighted Citation Impact
0.49
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article

Xenografted human microglia display diverse transcriptomic states in response to Alzheimer’s disease‐related Aβ pathology

Renzo Mancuso
2 citations
Alzheimer s & Dementia
Neuroinflammation and Neurodegeneration Mechanisms
0.49
article

Xenografted human microglia display diverse transcriptomic states in response to Alzheimer’s disease‐related Aβ pathology

Renzo Mancuso
article en
2 citations

Abstract

We have identified multiple transcriptomic cell states adopted by microglia in response to AD-related pathology, which should be taken into account in translational studies.

Alzheimer s & DementiaVol. 20(S1)
Vlaams Instituut voor Biotechnologie (BE)
Openalex Percentile: Top 32%
Neuroinflammation and Neurodegeneration Mechanisms
0.49
DOIOpen Access PDFOpenAlex
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Xenografted human microglia display diverse transcriptomic states in response to Alzheimer’s disease‐related Aβ pathology — Renzo Mancuso · Alzheimer s & Dementia (2024) | TGRS Research Map | TGRS