Comparison of cerebrospinal fluid and plasma oxidative stress biomarkers

Oxidative stress biomarker patterns differ across the AD continuum. RP demonstrates the most reliability, while TAC is the least. GSH and TBARS plasma and CSF measurements are negatively associated in the cognitively unimpaired, but not in the MCI population. Understanding oxidative biomarker evolution can enhance our comprehension of their role in AD and age-related disorders.

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Publication Details

Journal
Alzheimer s & Dementia
Published
2024-12-01
DOI
https://doi.org/10.1002/alz.085482
Primary Topic
Alzheimer's disease research and treatments
Type
article
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article

Comparison of cerebrospinal fluid and plasma oxidative stress biomarkers

Demetrios Kouretas, Eva Ntanasi, Zoi Skaperda, Eirini Mamalaki et al.
Alzheimer s & Dementia
Alzheimer's disease research and treatments
article

Comparison of cerebrospinal fluid and plasma oxidative stress biomarkers

Demetrios Kouretas, Eva Ntanasi, Zoi Skaperda, Eirini Mamalaki, Sokratis Charisis, Nikolaos Scarmeas, Adrián Noriega de la Colina
article en

Abstract

Oxidative stress biomarker patterns differ across the AD continuum. RP demonstrates the most reliability, while TAC is the least. GSH and TBARS plasma and CSF measurements are negatively associated in the cognitively unimpaired, but not in the MCI population. Understanding oxidative biomarker evolution can enhance our comprehension of their role in AD and age-related disorders.

Alzheimer s & DementiaVol. 20(S1)
Montreal Neurological Institute and Hospital (CA), University of Thessaly (GR), The University of Texas at San Antonio Health Science Center (US), National and Kapodistrian University of Athens (GR), Columbia University Irving Medical Center (US), Harokopio University of Athens (GR), Eginition Hospital (GR), McGill University (CA)
Openalex Percentile: Top 65%
Alzheimer's disease research and treatments
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Comparison of cerebrospinal fluid and plasma oxidative stress biomarkers — Demetrios Kouretas, Eva Ntanasi, et al. · Alzheimer s & Dementia (2024) | TGRS Research Map | TGRS