Exploring Sex‐Specific Accelerated Hippocampal Atrophy Across AD Stages beyond APOE‐e4 Assessment in Genetic Risk Evaluation
Our findings underscore the significance of genetic predisposition, especially functional APOE variants, in understanding AD progression and sex-specific trajectories. The results reveal varying atrophy patterns across disease stages, offering crucial insights for refining AD detection and tailoring interventions for more effective management.
Authors
- Hieab H.H. Adams (ORCID: https://orcid.org/0000-0003-3687-2508)
- Blanca Rodríguez‐Fernández (ORCID: https://orcid.org/0000-0002-5664-111X)
- Albert Rodrigo
- Arcadi Navarro (ORCID: https://orcid.org/0000-0003-2162-8246)
- Federica Anastasi (ORCID: https://orcid.org/0000-0002-9304-5421)
- Juan Domingo Gispert (ORCID: https://orcid.org/0000-0002-6155-0642)
- Tavia E. Evans (ORCID: https://orcid.org/0000-0003-2390-286X)
- Patricia Genius (ORCID: https://orcid.org/0000-0003-1836-5123)
- Natàlia Vilor‐Tejedor (ORCID: https://orcid.org/0000-0003-4935-6721)
Institutions
- Radboud University Nijmegen (NL)
- Erasmus MC (NL)
- Radboud University Medical Center (NL)
- Pasqual Maragall Foundation (ES)
- Barcelonaβeta Brain Research Center (ES)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2024-12-01
- DOI
- https://doi.org/10.1002/alz.086040
- Primary Topic
- Alzheimer's disease research and treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00