Signatures of resolution reprogramming in amyloid‐challenged microglia
We have demonstrated that RvE1 modulates inflammation in a mouse model and in a microglial cell line. Understanding the molecular signatures of resolution reprogramming in cells will be key to identifying prognostic indicators and molecular mechanisms of this unique understudied GPCR system and response in the brain.
Authors
- Galina Kondrikova
- Dariusz Pytel (ORCID: https://orcid.org/0000-0002-3849-7716)
- Eric D. Hamlett (ORCID: https://orcid.org/0000-0002-2900-7949)
Institutions
- Medical University of South Carolina (US)
- University of Charleston (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2024-12-01
- DOI
- https://doi.org/10.1002/alz.089644
- Primary Topic
- Neuroinflammation and Neurodegeneration Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 0.00