Whole‐Genome Sequencing Study in Koreans Identifies Novel Loci for Alzheimer Disease
We identified GWS and suggestive association for AD with several loci in Koreans and Japanese not previously observed in other populations. Our results provide additional insight into genetic mechanisms leading to AD and cognitive resilience, as well as emphasize the need for further genetic studies of East Asian populations.
Authors
- Moon-Il Kang (ORCID: https://orcid.org/0000-0001-5932-6804)
- John Farrell (ORCID: https://orcid.org/0000-0002-8726-5997)
- Jungsoo Gim (ORCID: https://orcid.org/0000-0002-6454-9751)
- Hyeonseul Park
- Gyungah Jun (ORCID: https://orcid.org/0000-0002-3230-8697)
- Kyu Yeong Choi (ORCID: https://orcid.org/0000-0003-1872-6953)
- Lindsay A. Farrer (ORCID: https://orcid.org/0000-0001-5533-4225)
- Kun Ho Lee
- Eun Hyun Seo (ORCID: https://orcid.org/0000-0002-4764-7464)
- Sarang Kang (ORCID: https://orcid.org/0000-0001-7808-0985)
- Sungho Won (ORCID: https://orcid.org/0000-0001-5751-5089)
- Congcong Zhu (ORCID: https://orcid.org/0000-0002-1657-8726)
Institutions
- Boston University (US)
- Seoul National University (KR)
- Chosun University (KR)
- Korea Brain Research Institute (KR)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2024-12-01
- DOI
- https://doi.org/10.1002/alz.089543
- Primary Topic
- Traditional Chinese Medicine Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00