Complement receptor 1 length polymorphism impacts glial functions relevant to Alzheimer’s disease

CR1 is an important component of microglial and astrocytic phagocytic activity; CR1*2-expressing cells showed increased phagocytosis of opsonised targets, providing clues to mechanism of association with AD risk.

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Publication Details

Journal
Alzheimer s & Dementia
Published
2024-12-01
DOI
https://doi.org/10.1002/alz.087385
Primary Topic
Complement system in diseases
Type
article
Field-Weighted Citation Impact
0.00
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article

Complement receptor 1 length polymorphism impacts glial functions relevant to Alzheimer’s disease

Paul Morgan, Nikoleta Daskoulidou
Alzheimer s & Dementia
Complement system in diseases
article

Complement receptor 1 length polymorphism impacts glial functions relevant to Alzheimer’s disease

Paul Morgan, Nikoleta Daskoulidou
article en

Abstract

CR1 is an important component of microglial and astrocytic phagocytic activity; CR1*2-expressing cells showed increased phagocytosis of opsonised targets, providing clues to mechanism of association with AD risk.

Alzheimer s & DementiaVol. 20(S1)
UK Dementia Research Institute (GB), Cardiff University (GB)
Good health and well-being
Openalex Percentile: Top 69%
Complement system in diseases
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Complement receptor 1 length polymorphism impacts glial functions relevant to Alzheimer’s disease — Paul Morgan, Nikoleta Daskoulidou · Alzheimer s & Dementia (2024) | TGRS Research Map | TGRS