Elevated iron levels in Alzheimer’s disease brain was partially due to increased cytosolic expression of hemoglobin in neurons
These results clarify that changes in iron proteins do occur in AD brain and open up a new area of research to understand the role of hemoglobin and haptoglobin in neuronal function.
Authors
- Blaine R. Roberts
- Madison E. Platt
- Catriona MacLean
- Ashley I. Bush (ORCID: https://orcid.org/0000-0001-8259-9069)
- Colin L. Masters (ORCID: https://orcid.org/0000-0003-3072-7940)
- Anne M. Roberts (ORCID: https://orcid.org/0000-0001-6730-8876)
- Ian E. Birchall (ORCID: https://orcid.org/0000-0002-0124-626X)
- Soumya Mukherjee (ORCID: https://orcid.org/0000-0001-5326-4008)
Institutions
- Emory University (US)
- The University of Melbourne (AU)
- Washington University in St. Louis (US)
- Florey Institute of Neuroscience and Mental Health (AU)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2024-12-01
- DOI
- https://doi.org/10.1002/alz.090319
- Primary Topic
- Alzheimer's disease research and treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00