Late‐life hemoglobin A1C is associated with postmortem neuropathology in older adults with and without diabetes

Using longitudinal A1C measures, we confirmed that A1C level is associated with cerebrovascular pathology and identified an inverse association with AD pathology. However, A1C variability over time showed no associations. Further studies are needed to understand the relationship of A1C to neuropathologies.

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Publication Details

Journal
Alzheimer s & Dementia
Published
2024-12-01
DOI
https://doi.org/10.1002/alz.090116
Primary Topic
Dementia and Cognitive Impairment Research
Type
article
Field-Weighted Citation Impact
0.00
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article

Late‐life hemoglobin A1C is associated with postmortem neuropathology in older adults with and without diabetes

David Alan Bennett, Ana W. Capuano, Zoe Arvanitakis, Roshni Biswas et al.
Alzheimer s & Dementia
Dementia and Cognitive Impairment Research
article

Late‐life hemoglobin A1C is associated with postmortem neuropathology in older adults with and without diabetes

David Alan Bennett, Ana W. Capuano, Zoe Arvanitakis, Roshni Biswas, Rupal I. Mehta
article en

Abstract

Using longitudinal A1C measures, we confirmed that A1C level is associated with cerebrovascular pathology and identified an inverse association with AD pathology. However, A1C variability over time showed no associations. Further studies are needed to understand the relationship of A1C to neuropathologies.

Alzheimer s & DementiaVol. 20(S1)
Rush University Medical Center (US), Rush University (US)
Good health and well-being
Openalex Percentile: Top 66%
Dementia and Cognitive Impairment Research
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