White blood cell types and tau deposition in the medial temporal lobe of cognitively normal older adults
Higher lymphocyte and lower monocyte values were associated with more MTL tau, particularly in amyloid-positive older adults suggesting a complex relationship between the peripheral immune system and early AD neuropathology.
Authors
- Meredith N. Braskie (ORCID: https://orcid.org/0000-0002-6439-4243)
- Koral V Wheeler
- Marylan Davison
- Mary M. Hand (ORCID: https://orcid.org/0000-0001-8266-2005)
- Victoria R Tennant
- Meral A. Tubi (ORCID: https://orcid.org/0000-0003-0435-8352)
- Kristine S. Yaffe (ORCID: https://orcid.org/0000-0003-0919-3825)
- Sid E. O’Bryant (ORCID: https://orcid.org/0000-0003-0582-5266)
- Arthur W. Toga (ORCID: https://orcid.org/0000-0003-1454-8643)
- Noelle Lee
- Jamie Terner
Institutions
- University of Southern California (US)
- University of North Texas (US)
- University of North Texas Health Science Center (US)
- University of California, San Francisco (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2024-12-01
- DOI
- https://doi.org/10.1002/alz.093280
- Primary Topic
- Neuroinflammation and Neurodegeneration Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 0.00