<i>Chlamydia pneumoniae</i> infection and inflammasome activation in Alzheimer’s retina: Correlations with disease status
Our findings reveal Cp infection in both AD retina and brain, coupled with inflammasome markers. This highlights a potential link to neurodegeneration in AD, offering avenues for therapeutic exploration, involving early antibiotic treatment or inflammasome attenuation.
Authors
- Lalita Subedi (ORCID: https://orcid.org/0000-0003-4851-7650)
- Keith L. Black (ORCID: https://orcid.org/0000-0002-0546-4934)
- Altan Rentsendorj (ORCID: https://orcid.org/0009-0001-4322-8107)
- Moshe Arditi (ORCID: https://orcid.org/0000-0001-9042-2909)
- Bhakta Prasad Gaire (ORCID: https://orcid.org/0000-0002-9738-6493)
- Timothy R. Crother (ORCID: https://orcid.org/0000-0001-8465-6127)
- Dieu‐Trang Fuchs
- Maya Koronyo‐Hamaoui (ORCID: https://orcid.org/0000-0003-2864-8442)
- Yosef Koronyo
- Natalie Swerdlow
Institutions
- Cedars-Sinai Medical Center (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2024-12-01
- DOI
- https://doi.org/10.1002/alz.087842
- Primary Topic
- Tryptophan and brain disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00