Reduced microglia Trem‐2 expression promotes LPS‐induced AD‐like pathology

These results emphasize the importance of Trem-2 in maintaining a healthy brain environment and suggest that targeting Trem-2 could be a potential therapeutic strategy for neurodegenerative diseases associated with microglia dysfunction.

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Publication Details

Journal
Alzheimer s & Dementia
Published
2024-12-01
DOI
https://doi.org/10.1002/alz.092583
Primary Topic
Neuroinflammation and Neurodegeneration Mechanisms
Type
article
Field-Weighted Citation Impact
0.00
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article

Reduced microglia Trem‐2 expression promotes LPS‐induced AD‐like pathology

Shahnawaz Ali Bhat
Alzheimer s & Dementia
Neuroinflammation and Neurodegeneration Mechanisms
article

Reduced microglia Trem‐2 expression promotes LPS‐induced AD‐like pathology

Shahnawaz Ali Bhat
article en

Abstract

These results emphasize the importance of Trem-2 in maintaining a healthy brain environment and suggest that targeting Trem-2 could be a potential therapeutic strategy for neurodegenerative diseases associated with microglia dysfunction.

Alzheimer s & DementiaVol. 20(S1)
Aligarh Muslim University (IN)
Openalex Percentile: Top 72%
Neuroinflammation and Neurodegeneration Mechanisms
DOIOpen Access PDFOpenAlex
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Reduced microglia Trem‐2 expression promotes LPS‐induced AD‐like pathology — Shahnawaz Ali Bhat · Alzheimer s & Dementia (2024) | TGRS Research Map | TGRS