Genetic analyses of the plasma proteome and metabolome from the same cohort pinpoint AD risk associated molecular phenotypes
Our study serves the first duo-omics post-transcriptional genetic study for studying AD risk effectors and can facilitate developing novel disease modifying treatments.
Authors
- Carlos Cruchaga (ORCID: https://orcid.org/0000-0002-5261-689X)
- Chengran Yang (ORCID: https://orcid.org/0000-0003-4577-5590)
- Yan V. Sun (ORCID: https://orcid.org/0000-0002-2838-1824)
- Ciyang Wang (ORCID: https://orcid.org/0000-0001-5253-0490)
- Lihua Wang (ORCID: https://orcid.org/0000-0002-0125-1544)
- Priyanka Gorijala (ORCID: https://orcid.org/0000-0001-7109-7362)
- David M. Holtzman (ORCID: https://orcid.org/0000-0002-3400-0856)
- Menghan Liu (ORCID: https://orcid.org/0009-0008-9902-5983)
- Jigyasha Timsina (ORCID: https://orcid.org/0000-0003-4794-9187)
- John C. Morris
Institutions
- Washington University in St. Louis (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2024-12-01
- DOI
- https://doi.org/10.1002/alz.085269
- Primary Topic
- Biological Research and Disease Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00