Lysosomal defects in <i>Grn</i> loss of function modulate microglial cell state and immune responses

Overall, these data reveal a novel link between lysosomal health and myeloid cell transcriptional and functional states.

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Publication Details

Journal
Alzheimer s & Dementia
Published
2024-12-01
DOI
https://doi.org/10.1002/alz.090872
Citations
1
Primary Topic
Neuroinflammation and Neurodegeneration Mechanisms
Type
article
Field-Weighted Citation Impact
0.25
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article

Lysosomal defects in Grn loss of function modulate microglial cell state and immune responses

Leon Tejwani, Gilbert Di Paolo
1 citations
Alzheimer s & Dementia
Neuroinflammation and Neurodegeneration Mechanisms
0.25
article

Lysosomal defects in Grn loss of function modulate microglial cell state and immune responses

Leon Tejwani, Gilbert Di Paolo
article en
1 citations

Abstract

Overall, these data reveal a novel link between lysosomal health and myeloid cell transcriptional and functional states.

Alzheimer s & DementiaVol. 20(S1)
Denali Therapeutics (United States) (US)
Openalex Percentile: Top 40%
Neuroinflammation and Neurodegeneration Mechanisms
0.25
DOIOpen Access PDFOpenAlex
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Lysosomal defects in <i>Grn</i> loss of function modulate microglial cell state and immune responses — Leon Tejwani, Gilbert Di Paolo · Alzheimer s & Dementia (2024) | TGRS Research Map | TGRS