Association of long‐term blood pressure variability with plasma neurofilament light underlies the comorbidity of Alzheimer's Disease and cerebral small vessel disease

Elevated BPV was linked with axonal damage, hippocampal atrophy, WMH progression, and cognitive decline. This finding suggests that the same risk factor may result in pathological changes in different brain regions and cognitive decline, which in turn may be associated with the comorbidity of AD and CSVD.