The role of common structural variants in Alzheimer’s disease
Using a novel SV calling pipeline, we identified multiple AD-related SVs, which provides additional insights into the genetic architecture of AD. Integration of omics data is warranted to explore the functional impact of these SVs.
Authors
- Anita L. DeStefano (ORCID: https://orcid.org/0000-0002-9335-2819)
- Songmi Lee (ORCID: https://orcid.org/0000-0001-6003-2336)
- Honghuang Lin (ORCID: https://orcid.org/0000-0003-3043-3942)
- Rui Xia (ORCID: https://orcid.org/0000-0003-2409-1181)
- Gina M. Peloso (ORCID: https://orcid.org/0000-0002-5355-8636)
- Fritz J. Sedlazeck (ORCID: https://orcid.org/0000-0001-6040-2691)
- Seung Hoan Choi (ORCID: https://orcid.org/0000-0002-2797-3190)
- Nancy L. Heard‐Costa (ORCID: https://orcid.org/0000-0001-9730-0306)
- Adam C. English (ORCID: https://orcid.org/0000-0003-2451-4375)
- Myriam Fornage (ORCID: https://orcid.org/0000-0003-0677-8158)
- Josh Bis
Institutions
- Boston University (US)
- University of Massachusetts Chan Medical School (US)
- Baylor College of Medicine (US)
- University of Washington (US)
- Baylor Genetics (US)
- The University of Texas Health Science Center at Houston (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2024-12-01
- DOI
- https://doi.org/10.1002/alz.092501
- Primary Topic
- Genomics and Rare Diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00