Advanced modeling of Alzheimer’s disease using human iPSC‐derived microglia and neurons carrying disease‐related mutations
Insights into how CD33<sup>ΔE2</sup> and R47H TREM2 mutations regulate microglial activity in an AD context can help to characterize them as potential therapeutic targets to arrest AD progression.
Authors
- Kenneth Thirstrup (ORCID: https://orcid.org/0000-0002-3181-6235)
- Berta Sanz Morello
- Benjamin Schmid (ORCID: https://orcid.org/0000-0002-0028-888X)
- Bjørn Holst (ORCID: https://orcid.org/0000-0002-4517-6881)
- SVEN FRANDSEN
- Elin Byman Shatri
Institutions
- Bioneer (Denmark) (DK)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2024-12-01
- DOI
- https://doi.org/10.1002/alz.088752
- Primary Topic
- Bioinformatics and Genomic Networks
- Type
- article
- Field-Weighted Citation Impact
- 0.00