Blood‐Brain Barrier Dynamics in Vascular Dementia: Unravelling the Tripartite Crosstalk between the Endothelium, Pericytes, and Microglia

Our approach underscores endothelial-pericyte crosstalk's crucial role in dementia. Integrating post-mortem tissues, fluid biomarkers, viral manipulations, and mouse models enriches understanding, guiding potential therapeutic interventions in vascular dementia.

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Publication Details

Journal
Alzheimer s & Dementia
Published
2024-12-01
DOI
https://doi.org/10.1002/alz.087126
Primary Topic
Neurological Disease Mechanisms and Treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

Blood‐Brain Barrier Dynamics in Vascular Dementia: Unravelling the Tripartite Crosstalk between the Endothelium, Pericytes, and Microglia

Axel Montagne
Alzheimer s & Dementia
Neurological Disease Mechanisms and Treatments
article

Blood‐Brain Barrier Dynamics in Vascular Dementia: Unravelling the Tripartite Crosstalk between the Endothelium, Pericytes, and Microglia

Axel Montagne
article en

Abstract

Our approach underscores endothelial-pericyte crosstalk's crucial role in dementia. Integrating post-mortem tissues, fluid biomarkers, viral manipulations, and mouse models enriches understanding, guiding potential therapeutic interventions in vascular dementia.

Alzheimer s & DementiaVol. 20(S1)
UK Dementia Research Institute (GB), University of Edinburgh (GB)
Openalex Percentile: Top 72%
Neurological Disease Mechanisms and Treatments
DOIOpen Access PDFOpenAlex
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Blood‐Brain Barrier Dynamics in Vascular Dementia: Unravelling the Tripartite Crosstalk between the Endothelium, Pericytes, and Microglia — Axel Montagne · Alzheimer s & Dementia (2024) | TGRS Research Map | TGRS