APOE3 Christchurch influences amyloid induced tau seeding and spreading via effects on microglia
APOE3ch influences the microglial response to Aβ plaques, which suppresses Aβ-induced tau seeding and spreading.
Authors
- Michael R. Strickland (ORCID: https://orcid.org/0000-0002-3899-5651)
- Chanung Wang (ORCID: https://orcid.org/0000-0002-6418-3809)
- Carla M. Yuede (ORCID: https://orcid.org/0000-0001-6362-4767)
- Jiyu Park (ORCID: https://orcid.org/0000-0002-6209-903X)
- Albert A. Davis (ORCID: https://orcid.org/0000-0003-2042-8445)
- Jason D. Ulrich (ORCID: https://orcid.org/0000-0002-4743-926X)
- Marco Colonna (ORCID: https://orcid.org/0000-0001-5222-4987)
- Yiyang Zhu (ORCID: https://orcid.org/0000-0002-0272-1915)
- Sihui Song (ORCID: https://orcid.org/0000-0001-5946-4799)
- G. Travis Tabor (ORCID: https://orcid.org/0000-0001-9640-3602)
- Samira Parhizkar (ORCID: https://orcid.org/0000-0001-5807-190X)
- David M. Holtzman (ORCID: https://orcid.org/0000-0002-3400-0856)
- Yun Chen (ORCID: https://orcid.org/0000-0003-0547-9463)
- Kevin Li (ORCID: https://orcid.org/0009-0005-4990-0071)
- Hong Jiang (ORCID: https://orcid.org/0000-0001-7188-5713)
- Jennifer Lord
Institutions
- Washington University in St. Louis (US)
- Hope Center for Neurological Disorders (US)
- Prevent Alzheimer’s Disease 2020 (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2024-12-01
- DOI
- https://doi.org/10.1002/alz.086126
- Primary Topic
- Alzheimer's disease research and treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00