Synergistic effects of α‐synuclein, tau, and amyloid pathology on mitophagy in dementia with Lewy bodies
Our study revealed complex interactions of α-synuclein, tau, and amyloid pathology on mitophagy alteration in DLB brains, highlighting different molecular mechanisms underlying α-synuclein- and tau-associated mitophagy alterations.
Authors
- Dennis W. Dickson (ORCID: https://orcid.org/0000-0001-7189-7917)
- Shunsuke Koga (ORCID: https://orcid.org/0000-0001-8868-9700)
- Michael G. Heckman (ORCID: https://orcid.org/0000-0003-3770-9331)
- Xu Hou (ORCID: https://orcid.org/0000-0003-3011-4378)
- Fabienne C. Fiesel (ORCID: https://orcid.org/0000-0002-1919-9676)
- Wolfdieter Springer (ORCID: https://orcid.org/0000-0002-1178-3149)
- Tyrique Richardson
Institutions
- WinnMed (US)
- Mayo Clinic in Florida (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2024-12-01
- DOI
- https://doi.org/10.1002/alz.092955
- Primary Topic
- Parkinson's Disease Mechanisms and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00