Dissecting the mechanisms of CASK deficiency on the clearance of Aβ in microglia
Our investigation revealed the critical roles of CASK in regulating microglial migration and phagocytic functions, particularly in the context of Aβ treatment. These findings necessitate further exploration into the nuanced functions of CASK in activated microglia, potentially offering insights into novel therapeutic avenues for AD.
Authors
- Y. Cho
- Irene Han‐Juo Cheng (ORCID: https://orcid.org/0000-0002-3737-3877)
- Justin Chang (ORCID: https://orcid.org/0000-0003-1454-794X)
- Yuhong Lin (ORCID: https://orcid.org/0009-0000-5267-665X)
Institutions
- National Yang Ming Chiao Tung University (TW)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2024-12-01
- DOI
- https://doi.org/10.1002/alz.086751
- Primary Topic
- Cell Adhesion Molecules Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00