Increasing the power of rare variant association analyses with common variant eQTLs in Alzheimer’s disease

Our approach is useful for discovering rare variation in genes that contribute to AD risk and heritability. This method can be flexibly incorporated into many existing analyses pipelines.

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Publication Details

Journal
Alzheimer s & Dementia
Published
2024-12-01
DOI
https://doi.org/10.1002/alz.093228
Primary Topic
Bioinformatics and Genomic Networks
Type
article
Field-Weighted Citation Impact
0.00
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article

Increasing the power of rare variant association analyses with common variant eQTLs in Alzheimer’s disease

William S. Bush, Yuchen Yang
Alzheimer s & Dementia
Bioinformatics and Genomic Networks
article

Increasing the power of rare variant association analyses with common variant eQTLs in Alzheimer’s disease

William S. Bush, Yuchen Yang
article en

Abstract

Our approach is useful for discovering rare variation in genes that contribute to AD risk and heritability. This method can be flexibly incorporated into many existing analyses pipelines.

Alzheimer s & DementiaVol. 20(S1)
Case Western Reserve University (US)
Openalex Percentile: Top 78%
Bioinformatics and Genomic Networks
DOIOpen Access PDFOpenAlex
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Increasing the power of rare variant association analyses with common variant eQTLs in Alzheimer’s disease — William S. Bush, Yuchen Yang · Alzheimer s & Dementia (2024) | TGRS Research Map | TGRS