Unraveling the molecular mechanisms underlying neocortical tau propagation in Alzheimer’s disease to reveal novel insights into clinical heterogeneity
These findings provide further insights into multiple molecular mechanisms potentially involved in disease progression, highlight targets for early intervention, and improve patient subtyping, which is critical for developing precision medicines.
Authors
- Li Shen (ORCID: https://orcid.org/0000-0002-5190-2851)
- Diede W. M. Broekaart (ORCID: https://orcid.org/0000-0002-4842-0659)
- Aarthi Ramakrishnan (ORCID: https://orcid.org/0000-0002-6329-6502)
- Carolyn W. Zhu (ORCID: https://orcid.org/0000-0002-2318-715X)
- Anjalika Chongtham (ORCID: https://orcid.org/0000-0001-8437-3899)
- Joon Ho Seo
- Ana C. Pereira (ORCID: https://orcid.org/0000-0003-2524-7969)
- Mary Sano
- M. Carmen Fariñas
Institutions
- James J. Peters VA Medical Center (US)
- Icahn School of Medicine at Mount Sinai (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2024-12-01
- DOI
- https://doi.org/10.1002/alz.084995
- Primary Topic
- Computational Drug Discovery Methods
- Type
- article
- Field-Weighted Citation Impact
- 0.00