Ingestion of Ubiquitous Environmental Metal‐Metalloid Neurotoxicants Lead, Cadmium, or Arsenic in Drinking Water Results in Brain Accumulation And Alters the Alzheimer’s Disease Exposome
MODEL-AD mice exposed to Pb, Cd, or As accumulate metal/metalloid toxicants in blood and brain and showed toxicant-specific alterations in AD-relevant gene expression and gene module profiles.
Authors
- Kevin P. Kotredes (ORCID: https://orcid.org/0000-0001-7874-4139)
- Nicola Lupoli
- Olga Minaeva (ORCID: https://orcid.org/0000-0002-7911-6510)
- Gareth R. Howell (ORCID: https://orcid.org/0000-0003-0565-6474)
- Juliet A. Moncaster (ORCID: https://orcid.org/0000-0002-7849-4325)
- Lee E. Goldstein (ORCID: https://orcid.org/0000-0001-8419-9800)
Institutions
- Boston University (US)
- Jackson Laboratory (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2024-12-01
- DOI
- https://doi.org/10.1002/alz.093261
- Citations
- 1
- Primary Topic
- Heavy Metal Exposure and Toxicity
- Type
- article
- Field-Weighted Citation Impact
- 0.31