Vascular pathology: a key neuropathological feature in young and middle age individuals
Our data show that AD neuropathological changes can begin in mid-age and corroborate findings from other series predominantly involving older Caucasians with high educational attainment, which have demonstrated the role of vascular pathology in cognitive impairment. As vascular risks are preventable, implementing aggressive measures to reduce these factors may impact the prevalence of cognition-related dysfunction.
Authors
- Lea T. Grinberg (ORCID: https://orcid.org/0000-0002-6809-0618)
- Renata Elaine Paraízo Leite (ORCID: https://orcid.org/0000-0002-5878-398X)
- Roberta Diehl Rodriguez (ORCID: https://orcid.org/0000-0002-6544-7861)
- Carlos Augusto Pasqualucci (ORCID: https://orcid.org/0000-0001-6608-2473)
- Eduardo Ferriolli (ORCID: https://orcid.org/0000-0002-5028-2451)
- Cláudia Kimie Suemoto (ORCID: https://orcid.org/0000-0002-5942-4778)
- Ricardo Nitríni (ORCID: https://orcid.org/0000-0002-5721-1525)
- Sônia Maria Dozzi Brucki (ORCID: https://orcid.org/0000-0002-8303-6732)
- Renata Eloah de Lucena Ferretti‐Rebustini (ORCID: https://orcid.org/0000-0001-5615-8489)
- Wilson Jacob Filho (ORCID: https://orcid.org/0000-0003-2290-4492)
- Karen Luiza Ramos Socher (ORCID: https://orcid.org/0000-0001-9585-4989)
Institutions
- Universidade de São Paulo (BR)
- University of California, San Francisco (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2024-12-01
- DOI
- https://doi.org/10.1002/alz.093400
- Primary Topic
- Dementia and Cognitive Impairment Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00