Multi‐ancestry Genome‐wide Gene‐Vascular Risk Factors Interaction Analyses in Alzheimer’s Disease
We identified novel candidate genes that interact with CVRFs on AD in multi-ethnic cohorts. Understanding the interplay between genes, CVRFs, and AD has the potential to reveal novel molecular targets for prevention and treatment for AD.
Authors
- Martin Medrano (ORCID: https://orcid.org/0000-0003-3673-9088)
- Giuseppe Tosto (ORCID: https://orcid.org/0000-0001-7075-8245)
- Adam M. Brickman (ORCID: https://orcid.org/0000-0002-5125-8226)
- Zuoqiao Cui
- Vilas Menon (ORCID: https://orcid.org/0000-0002-4096-8601)
- Sarah Biber
- Diones Rivera Mejía (ORCID: https://orcid.org/0000-0001-5935-8005)
- Julie A. Schneider (ORCID: https://orcid.org/0000-0002-9482-1752)
- Ivonne Z. Jiménez‐Velázquez (ORCID: https://orcid.org/0000-0002-9943-1657)
- Jaeyoon Chung (ORCID: https://orcid.org/0000-0002-6431-9454)
- Lindsay A. Farrer (ORCID: https://orcid.org/0000-0001-5533-4225)
- Philip L. De Jager (ORCID: https://orcid.org/0000-0002-8057-2505)
- Walter A. Kukull (ORCID: https://orcid.org/0000-0001-8761-9014)
- Zhenwei Song (ORCID: https://orcid.org/0000-0001-8547-7462)
- Çağhan Kızıl (ORCID: https://orcid.org/0000-0002-8164-9762)
- Annie Lee (ORCID: https://orcid.org/0000-0003-3726-6024)
- Richard P Mayeux (ORCID: https://orcid.org/0000-0001-6519-9696)
- Badri Narayan Vardarajan (ORCID: https://orcid.org/0000-0002-5560-4085)
- Dolly Reyes‐Dumeyer (ORCID: https://orcid.org/0000-0003-3572-8248)
- Rafael Lantigua (ORCID: https://orcid.org/0000-0003-4854-7331)
- Jesse Mez (ORCID: https://orcid.org/0000-0003-1438-5442)
- David A. Bennett
- Yanling Wang (ORCID: https://orcid.org/0009-0003-0061-9946)
Institutions
- Boston University (US)
- Rush University Medical Center (US)
- NewYork–Presbyterian Hospital (US)
- Pontificia Universidad Católica Madre y Maestra (DO)
- University of Puerto Rico System (PR)
- University of Washington (US)
- Columbia University Irving Medical Center (US)
- New York Hospital Queens (US)
- Universidad Nacional Pedro Henríquez Ureña (DO)
- Framingham Heart Study (US)
- Takeda (United States) (US)
- Columbia University (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2024-12-01
- DOI
- https://doi.org/10.1002/alz.093041
- Primary Topic
- Genetic Associations and Epidemiology
- Type
- article
- Field-Weighted Citation Impact
- 0.00