The prefrontal cortex of homozygous ε3 APOE carriers with local African ancestry has fewer transcripts compared to individuals with local European ancestry

These data support the hypothesis that the lower expression of APOEε3 may be part of the explanation for the reduced African risk of DA in homozygous individuals.

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Publication Details

Journal
Alzheimer s & Dementia
Published
2024-12-01
DOI
https://doi.org/10.1002/alz.093090
Primary Topic
Williams Syndrome Research
Type
article
Field-Weighted Citation Impact
0.00
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article

The prefrontal cortex of homozygous ε3 APOE carriers with local African ancestry has fewer transcripts compared to individuals with local European ancestry

Nathália Alves dos Santos, Cláudia Kimie Suemoto, Michel Satya Naslavsky, Luciana Amaral Haddad et al.
Alzheimer s & Dementia
Williams Syndrome Research
article

The prefrontal cortex of homozygous ε3 APOE carriers with local African ancestry has fewer transcripts compared to individuals with local European ancestry

Nathália Alves dos Santos, Cláudia Kimie Suemoto, Michel Satya Naslavsky, Luciana Amaral Haddad, Renata Eloah de Lucena Ferretti‐Rebustini
article en

Abstract

These data support the hypothesis that the lower expression of APOEε3 may be part of the explanation for the reduced African risk of DA in homozygous individuals.

Alzheimer s & DementiaVol. 20(S1)
Universidade de São Paulo (BR)
Openalex Percentile: Top 72%
Williams Syndrome Research
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