Genome‐wide DNA methylation in early‐onset dementias brain tissue and lymphoblastoid cell lines
This study enhances our understanding about the biological pathways that are associated with neurodegeneration, describes differential methylation patterns, and suggests LCLs are a potential cell model for studying neurodegenerative diseases in early clinical phases.
Authors
- David Hervás (ORCID: https://orcid.org/0000-0003-0635-4961)
- Oscar Ramos‐Campoy (ORCID: https://orcid.org/0000-0003-3922-6827)
- Albert Lladó (ORCID: https://orcid.org/0000-0002-5066-4150)
- Mircea Balasa (ORCID: https://orcid.org/0000-0002-1795-4228)
- Raquel Sánchez‐Valle (ORCID: https://orcid.org/0000-0001-7750-896X)
- Sergi Borrego‐Écija (ORCID: https://orcid.org/0000-0003-2557-0010)
- Beatríz Bosch (ORCID: https://orcid.org/0000-0002-6094-0024)
- Anna Antonell (ORCID: https://orcid.org/0000-0002-3286-8459)
- Juan Sandoval (ORCID: https://orcid.org/0000-0002-5100-973X)
- Guadalupe Fernández‐Villullas (ORCID: https://orcid.org/0000-0002-0569-1344)
- Laura Fort‐Aznar (ORCID: https://orcid.org/0000-0002-3869-7494)
- Fermín Moreno (ORCID: https://orcid.org/0000-0001-5200-3164)
- Aina Comas‐Albertí
- Laura Molina
Institutions
- Biogipuzkoa Health Research Institute (ES)
- Hospital Clínic de Barcelona (ES)
- Fundació Clínic per a la Recerca Biomèdica (ES)
- Consorci Institut D'Investigacions Biomediques August Pi I Sunyer (ES)
- Universitat Politècnica de València (ES)
- Universitat de Barcelona (ES)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2024-12-01
- DOI
- https://doi.org/10.1002/alz.088732
- Primary Topic
- Epigenetics and DNA Methylation
- Type
- article
- Field-Weighted Citation Impact
- 0.00