Differential Association of Follicle‐Stimulating Hormone and Estrogen with Disease Severity and Cerebral Amyloid Deposition in Alzheimer’s Disease Spectrum
This study provides insights into the link between FSH, neuropsychological AD stages, and cerebral Aβ deposition in post-menopausal women, highlighting FSH's potential role as a biomarker. In contrast, such associations were not observed for E2. Further research is needed to unravel the underlying mechanisms and explore therapeutic avenues targeting hormonal pathways in AD.
Authors
- Hyun Kook Lim (ORCID: https://orcid.org/0000-0001-8742-3409)
- Ki‐Hyun Baek (ORCID: https://orcid.org/0000-0002-4097-1077)
- Chaiho Jeong (ORCID: https://orcid.org/0000-0002-2914-2278)
- Dong Woo Kang (ORCID: https://orcid.org/0000-0003-3289-075X)
- Yoo Hyun Um (ORCID: https://orcid.org/0000-0002-3403-4140)
- Chang Uk Lee (ORCID: https://orcid.org/0000-0001-6398-7330)
- Sunghwan Kim (ORCID: https://orcid.org/0000-0001-6455-4369)
- Sheng‐Min Wang (ORCID: https://orcid.org/0000-0002-1707-9435)
Institutions
- The Catholic University of Korea St. Vincent's Hospital (KR)
- The Catholic University of Korea Yeouido St. Mary's Hospital (KR)
- The Catholic University of Korea Seoul St. Mary's Hospital (KR)
- Catholic University of Korea (KR)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2024-12-01
- DOI
- https://doi.org/10.1002/alz.088504
- Primary Topic
- Phytoestrogen effects and research
- Type
- article
- Field-Weighted Citation Impact
- 0.00