Analyzing the expression of candidate genes in whole blood of autosomal dominant Alzheimer’s Disease
Mutation carriers show some DEGs in whole blood, even in the asymptomatic stage. FXYD5 and MAPT genes show a consistent up-regulation in both SMC and AMC, suggesting it could be further validated as a possible genetic biomarker in whole blood of ADAD.
Authors
- Oscar Ramos‐Campoy (ORCID: https://orcid.org/0000-0003-3922-6827)
- Agnès Pérez‐Millan (ORCID: https://orcid.org/0000-0002-3006-9792)
- Albert Lladó (ORCID: https://orcid.org/0000-0002-5066-4150)
- Mircea Balasa (ORCID: https://orcid.org/0000-0002-1795-4228)
- Raquel Sánchez‐Valle (ORCID: https://orcid.org/0000-0001-7750-896X)
- Beatríz Bosch (ORCID: https://orcid.org/0000-0002-6094-0024)
- Guadalupe Fernández‐Villullas (ORCID: https://orcid.org/0000-0002-0569-1344)
- Roger Puey
- Alba Gómez‐Núñez
- Aina Comas‐Albertí
- Anna Antonell
Institutions
- Hospital Clínic de Barcelona (ES)
- Fundació Clínic per a la Recerca Biomèdica (ES)
- Consorci Institut D'Investigacions Biomediques August Pi I Sunyer (ES)
- Universitat de Barcelona (ES)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2024-12-01
- DOI
- https://doi.org/10.1002/alz.089842
- Primary Topic
- Bioinformatics and Genomic Networks
- Type
- article
- Field-Weighted Citation Impact
- 0.00