Characterization of Alzheimer’s Disease‐Related Plasma Biomarkers in Gammaherpesvirus Infected Common Marmosets
The enhancement of plasma biomarkers, such as NfL and tau, in gammaherpesvirus infected aged marmosets suggests that viral infection may contribute to AD-related pathology and neurodegeneration. Investigation is ongoing in additional animals to further characterize the relationship of plasma biomarkers to viral infection and viral load. The common marmoset is a unique translational model that allows for the investigation of AD and the potential role that herpesviruses play in disease manifestation and progression.
Authors
- Stacey L. Piotrowski
- Gregory W. Carter (ORCID: https://orcid.org/0000-0002-2834-8186)
- Heather Lyons Narver
- Afonso C. Silva (ORCID: https://orcid.org/0000-0002-6105-7567)
- Steven Jacobson (ORCID: https://orcid.org/0000-0003-3127-1287)
- Stacey J. Sukoff Rizzo (ORCID: https://orcid.org/0000-0002-1460-8127)
- Brianne Stein
- Allison Tucker (ORCID: https://orcid.org/0009-0009-2540-3467)
- Julia Oluoch
- Ting Zhang (ORCID: https://orcid.org/0000-0001-6133-1629)
- Lauren K Hayrynen Schaeffer
- Amanda J. Lee
Institutions
- University of Pittsburgh (US)
- Purdue University West Lafayette (US)
- National Institute of Neurological Disorders and Stroke (US)
- Jackson Laboratory (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2024-12-01
- DOI
- https://doi.org/10.1002/alz.092787
- Primary Topic
- Medicinal Plant Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00