Investigating the microvascular dysfunction in the Frontotemporal Dementia using a progranulin‐deficient mice model

This study shows that the BBB is damaged in PGRN-deficient mice, accompanied by microvascular dysfunction and hypoperfusion. The data suggest that PGRN-deficient mice could be an ideal model to investigate vascular contributions to FTD.

Authors

Sofia Franciosa
Supriya Chakraborty (ORCID: https://orcid.org/0000-0001-9301-2649)
Oliver Bracko (ORCID: https://orcid.org/0000-0002-9414-6590)

Institutions

University of Miami (US)

Publication Details

Journal: Alzheimer s & Dementia
Published: 2024-12-01
DOI: https://doi.org/10.1002/alz.093422
Citations: 1
Primary Topic: Amyotrophic Lateral Sclerosis Research
Type: article
Field-Weighted Citation Impact: 0.37

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article

Investigating the microvascular dysfunction in the Frontotemporal Dementia using a progranulin‐deficient mice model

Sofia Franciosa, Supriya Chakraborty, Oliver Bracko

Dec 1, 2024

1 citations

Alzheimer s & Dementia

Amyotrophic Lateral Sclerosis Research

0.37

article

Investigating the microvascular dysfunction in the Frontotemporal Dementia using a progranulin‐deficient mice model

Sofia Franciosa, Supriya Chakraborty, Oliver Bracko

December 1, 2024article en

1 citations

Abstract

Alzheimer s & DementiaVol. 20(S1)

University of Miami (US)

Openalex Percentile: Top 32%

Amyotrophic Lateral Sclerosis Research

0.37

DOI Open Access PDF OpenAlex

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Investigating the microvascular dysfunction in the Frontotemporal Dementia using a progranulin‐deficient mice model — Sofia Franciosa, Supriya Chakraborty, et al. · Alzheimer s & Dementia (2024) | TGRS Research Map | TGRS