The effect of estrogen signaling modulation on female‐specific microglial heterogeneity in the mouse hippocampus
Such skewing of microglia towards reactive phenotype suggests that loss of estrogen- ERα signaling may encourage "priming" of microglia to transition to the stage 1 DAM phenotype, which is then more susceptible to becoming "reactive" DAMs (stage 2 DAMs).
Authors
- Sung-Hwan Ko (ORCID: https://orcid.org/0009-0000-8572-702X)
Institutions
- University of Oklahoma Health Sciences Center (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2024-12-01
- DOI
- https://doi.org/10.1002/alz.090388
- Citations
- 1
- Primary Topic
- Neuroinflammation and Neurodegeneration Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 0.25