Spatially defined transcriptomic changes across the hippocampus of J20 mice
Overall, these results demonstrate region-specific transcriptional changes in the hippocampus of J20 mice compared with WT controls. DEGs and networks of co-expressed genes were found to be associated with disease-associated pathways, giving insight into region-specific pathological changes with disease.
Authors
- Jon T. Brown (ORCID: https://orcid.org/0000-0001-5269-7661)
- Clive Ballard (ORCID: https://orcid.org/0000-0003-0022-5632)
- Katie Lunnon (ORCID: https://orcid.org/0000-0001-7570-6065)
- Millie Sander
Institutions
- University of Exeter (GB)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2024-12-01
- DOI
- https://doi.org/10.1002/alz.092346
- Primary Topic
- interferon and immune responses
- Type
- article
- Field-Weighted Citation Impact
- 0.00